USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: FYB_HUMAN USC-OGP 2-DE database:  FYB_HUMAN FYB_HUMAN General information about the entry View entry in simple text format Entry name FYB_HUMAN Primary accession number O15117 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=FYN-binding protein; AltName: Full=Adhesion and degranulation promoting adaptor protein; Short=ADAP; AltName: Full=FYB-120/130; Short=p120/p130; AltName: Full=FYN-T-binding protein; AltName: Full=SLAP-130; AltName: Full=SLP-76-associated phosphoprotein;. Gene name Name=FYB Synonyms=SLAP130 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0192: pI=4.90; Mw=25341 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0781: pI=5.94; Mw=30102 SPOT OGP-0782: pI=5.96; Mw=30063 Cross-references UniProtKB/Swiss-Prot O15117; FYB_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name FYB_HUMAN Primary accession number O15117 Secondary accession number(s) A8K2Y8 B4DLN2 E9PBV9 O00359 Q9NZI9 Sequence was last modified on  November 24, 2009 (version 2) Annotations were last modified on  March 15, 2017 (version 163) Name and origin of the protein Description RecName: Full=FYN-binding protein; AltName: Full=Adhesion and degranulation promoting adaptor protein; Short=ADAP; AltName: Full=FYB-120/130; Short=p120/p130; AltName: Full=FYN-T-binding protein; AltName: Full=SLAP-130; AltName: Full=SLP-76-associated phosphoprotein; Gene name Name=FYB Synonyms=SLAP130 Encoded on Name=FYB; Synonyms=SLAP130 Keywords 3D-structure; Acetylation; Alternative splicing; Cell junction; Coiled coil; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; SH3 domain. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF001862; AAB62226.1; -; mRNA EMBL U93049; AAC51300.1; -; mRNA EMBL AF198052; AAF62400.1; -; mRNA EMBL AK290403; BAF83092.1; -; mRNA EMBL AK297077; BAG59594.1; -; mRNA EMBL AC008964; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC010633; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC025471; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471119; EAW55984.1; -; Genomic_DNA EMBL BC117449; AAI17450.1; -; mRNA EMBL BC143645; AAI43646.1; -; mRNA CCDS CCDS47200.1; -. [O15117-1]; . CCDS CCDS54848.1; -. [O15117-2]; . CCDS CCDS58945.1; -. [O15117-3]; . RefSeq NP_001230022.1; NM_001243093.1. [O15117-3]; . RefSeq NP_001456.3; NM_001465.4. [O15117-2]; . RefSeq NP_955367.1; NM_199335.3. [O15117-1]; . RefSeq XP_006714527.1; XM_006714464.2. [O15117-2]; . RefSeq XP_006714528.1; XM_006714465.2. [O15117-2]; . RefSeq XP_006714529.1; XM_006714466.2. [O15117-2]; . RefSeq XP_011512310.1; XM_011514008.2. [O15117-3]; . RefSeq XP_011512311.1; XM_011514009.1. [O15117-2]; . RefSeq XP_011512312.1; XM_011514010.1. [O15117-2]; . UniGene Hs.370503; -; . UniGene Hs.691768; -; . PDB 1RI9; NMR; -; A=683-771 PDB 2GTJ; NMR; -; A=486-579 PDB 2GTO; NMR; -; A=486-579 PDBsum 1RI9; -; . PDBsum 2GTJ; -; . PDBsum 2GTO; -; . ProteinModelPortal O15117; -; . SMR O15117; -; . BioGrid 108809; 13; . DIP DIP-42204N; -; . IntAct O15117; 26; . MINT MINT-1176058; -; . iPTMnet O15117; -; . PhosphoSitePlus O15117; -; . BioMuta FYB; -; . OGP O15117; -; . MaxQB O15117; -; . PeptideAtlas O15117; -; . PRIDE O15117; -; . Ensembl ENST00000351578; ENSP00000316460; ENSG00000082074. [O15117-1]; . Ensembl ENST00000505428; ENSP00000427114; ENSG00000082074. [O15117-2]; . Ensembl ENST00000512982; ENSP00000425845; ENSG00000082074. [O15117-3]; . Ensembl ENST00000515010; ENSP00000426346; ENSG00000082074. [O15117-1]; . GeneID 2533; -; . KEGG hsa:2533; -; . UCSC uc003jls.4; human. [O15117-1]; . CTD 2533; -; . DisGeNET 2533; -; . GeneCards FYB; -; . H-InvDB HIX0024785; -; . HGNC HGNC:4036; FYB; . HPA CAB025336; -; . HPA HPA026796; -; . MIM 602731; gene; . neXtProt NX_O15117; -; . OpenTargets ENSG00000082074; -; . PharmGKB PA28452; -; . GeneTree ENSGT00530000063460; -; . HOGENOM HOG000008686; -; . HOVERGEN HBG005774; -; . InParanoid O15117; -; . KO K17698; -; . OMA SWGILKM; -; . OrthoDB EOG091G04X1; -; . PhylomeDB O15117; -; . TreeFam TF337003; -; . Reactome R-HSA-202433; Generation of second messenger molecules; . Reactome R-HSA-391160; Signal regulatory protein (SIRP) family interactions; . SignaLink O15117; -; . SIGNOR O15117; -; . ChiTaRS FYB; human; . EvolutionaryTrace O15117; -; . GeneWiki FYB; -; . GenomeRNAi 2533; -; . PMAP-CutDB O15117; -; . PRO PR:O15117; -; . Proteomes UP000005640; Chromosome 5; . Bgee ENSG00000082074; -; . CleanEx HS_FYB; -; . ExpressionAtlas O15117; baseline and differential; . Genevisible O15117; HS; . GO GO:0015629; C:actin cytoskeleton; TAS:UniProtKB; . GO GO:0030054; C:cell junction; IEA:UniProtKB-SubCell; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0005634; C:nucleus; TAS:ProtInc; . GO GO:0005886; C:plasma membrane; IBA:GO_Central; . GO GO:0005102; F:receptor binding; TAS:UniProtKB; . GO GO:0006955; P:immune response; TAS:ProtInc; . GO GO:0035556; P:intracellular signal transduction; TAS:ProtInc; . GO GO:0006607; P:NLS-bearing protein import into nucleus; TAS:ProtInc; . GO GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl; . GO GO:0006468; P:protein phosphorylation; TAS:ProtInc; . GO GO:0007165; P:signal transduction; TAS:ProtInc; . GO GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome; . InterPro IPR030635; FYB; . InterPro IPR029294; hSH3; . InterPro IPR011511; SH3_2; . InterPro IPR001452; SH3_domain; . PANTHER PTHR16830:SF18; PTHR16830:SF18; 1; . Pfam PF14603; hSH3; 1; . Pfam PF07653; SH3_2; 1; . SMART SM00326; SH3; 1; . SUPFAM SSF50044; SSF50044; 2; .

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